Interleukins adapt to parasites

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Interleukins adapt to parasites

TLR choreography Pathogen-sensing Toll-like receptors (TLRs) must be deployed accurately. Here, Fukui et al. show how finely tuned these receptors are. Tweaking a single amino acid in a TLR-trafficking molecule determined whether the signal was green or red for nucleic acid–sensing TLRs (page 1339). TLR7 and TLR9 recognize viral nucleic acids—RNA and DNA, respectively—in endolysosomes. By seque...

متن کامل

Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice

Trypanosoma brucei is an extracellular parasite that causes sleeping sickness. In mammalian hosts, trypanosomes are thought to exist in two major niches: early in infection, they populate the blood; later, they breach the blood-brain barrier. Working with a well-established mouse model, we discovered that adipose tissue constitutes a third major reservoir for T. brucei. Parasites from adipose t...

متن کامل

Knowledge Adaptation: Teaching to Adapt

Domain adaptation is crucial in many real-world applications where the distribution of the training data differs from the distribution of the test data. Previous Deep Learning-based approaches to domain adaptation need to be trained jointly on source and target domain data and are therefore unappealing in scenarios where models need to be adapted to a large number of domains or where a domain i...

متن کامل

Agents adapt to majority behaviours

Agents within a group can have different perceptions of their working environment and autonomously fulfil their goals. However, they can be aware of beliefs and goals of the group as well as other members so that they can adjust their behaviours accordingly. To model these agents, we explicitly include knowledge commonly shared by the group and that obtained from other agents. By avoiding actio...

متن کامل

Adapting to Learn, Learning to Adapt

The Next Big Thing Adaptive, or personalized, learning is becoming the next big thing in online education. By providing each student with a custom, personalized path through courses and tracking both content covered and level of attained mastery, adaptive learning platforms hold great promise for enhancing student learning and success. Adaptive course content is organized as a set of nodes in a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 2009

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.2066iti4